Author(s)
Content
Video Abstract (AI generated) (01:57) Paper Preprint NeuroImageA fundamental question in systems neuroscience is how endogenous neuronal activity self-organizes during particular brain states. Recent neuroimaging studies have revealed systematic relationships between resting-state and task-induced functional connectivity (FC). In particular, continuous task studies, such as movie watching, speak to alterations in coupling among cortical regions and enhanced fluctuations in FC compared to resting-state. This suggests that FC may reflect systematic and large-scale reorganization of functionally integrated responses while subjects are watching movies. In this study, we characterized fluctuations in FC during resting-state and movie-watching conditions. We found that the FC patterns induced systematically by movie-watching can be explained with a single principal component. These condition-specific FC fluctuations overlapped with inter-subject synchronization patterns in occipital and temporal brain regions. However, unlike inter-subject synchronization, condition-specific FC patterns contained increased correlations within frontal brain regions and reduced correlations between frontal-parietal brain regions. We investigated the condition-specific functional variations as a shorter time scale, using time-resolved FC. The time-resolved FC showed condition-specificity over time, notably when subjects were also watching the same and different movie scenes. To explain the self-organisation of whole-brain FC through the alterations in local dynamics, we used a large-scale computational model. We found that the condition-specific reorganization of FC could be explained by local changes that engendered changes in FC among higher-order association regions, mainly in frontal parietal cortices.
More Projects
Loren Frank
13 views • 2 years ago
Global Immunotalks
390 views • 3 years ago
Laurel Yohe
2 views • 2 years ago
Global Immunotalks
130 views • 3 years ago
Jignesh H. Parmar
0 views • 2 years ago
Winston A. Haynes
0 views • 2 years ago
Noam Mazor
0 views • 2 years ago
Global Immunotalks
182 views • 3 years ago
Cem Yuksel
345 views • 2 years ago
Oscar Gonzalez-Recio
3 views • 2 years ago
Please pick a style:
Karl Friston. (2021, Oct 24).Distinct Modes of Functional Connectivity induced by Movie-Watching[Video]. Scitok. https://scitok.com/project/p/059787bf
DemirtaĹź Murat. "Distinct Modes of Functional Connectivity induced by Movie-Watching" Scitok, uploaded by Friston Karl, 24 Oct, 2021, https://scitok.com/project/p059787bf
Karl Friston. "Distinct Modes of Functional Connectivity induced by Movie-Watching" Scitok. (Oct 24, 2021). https://scitok.com/project/p/059787bf
Karl Friston (Oct 24, 2021). Distinct Modes of Functional Connectivity induced by Movie-Watching Scitok. https://scitok.com/project/p/059787bf
Karl Friston. Distinct Modes of Functional Connectivity induced by Movie-Watching[video]. 2021 Oct 24. https://scitok.com/project/p/059787bf
@online{al2006link, title={ Distinct Modes of Functional Connectivity induced by Movie-Watching }, author={ Friston, Karl }, organization={Scitok}, month={ Oct }, day={ 24 }, year={ 2021 }, url = {https://scitok.com/project/p/059787bf}, }