Author(s)
Kirstie J. Whitaker
Published 7 Projects
Neuroscience Structure 1. Introduction Gene Expression Schizophrenia
Petra E Vértes
Published 13 Projects
Neuroscience Psychiatry And Clinical Psychology Structure 1. Introduction Natural Language Processing
Raymond J. Dolan
Published 5 Projects
Neuroscience 1. Introduction Gene Expression Schizophrenia Mri
the NSPN Consortium
Published 5 Projects
Neuroscience 1. Introduction Gene Expression Schizophrenia Mri
Edward T. Bullmore
Published 11 Projects
Neuroscience Structure 1. Introduction Gene Expression Schizophrenia
Content
Macroscopic cortical networks are important for cognitive function, but it remains challenging to construct anatomically plausible individual structural connectomes from human neuroimaging. We introduce a new technique for cortical network mapping, based on inter-regional similarity of multiple morphometric parameters measured using multimodal MRI. In three cohorts (two human, one macaque), we find that the resulting morphometric similarity networks (MSNs) have a complex topological organisation comprising modules and high-degree hubs. Human MSN modules recapitulate known cortical cytoarchitectonic divisions, and greater inter-regional morphometric similarity was associated with stronger inter-regional co-expression of genes enriched for neuronal terms. Comparing macaque MSNs to tract-tracing data confirmed that morphometric similarity was related to axonal connectivity. Finally, variation in the degree of human MSN nodes accounted for about 40% of between-subject variability in IQ. Morphometric similarity mapping provides a novel, robust and biologically plausible approach to understanding how human cortical networks underpin individual differences in psychological functions.
More Projects
Loren Frank
13 views • 2 years ago
Global Immunotalks
390 views • 2 years ago
Laurel Yohe
2 views • 2 years ago
Global Immunotalks
130 views • 2 years ago
Jignesh H. Parmar
0 views • 1 year ago
Winston A. Haynes
0 views • 1 year ago
Noam Mazor
0 views • 1 year ago
Global Immunotalks
182 views • 2 years ago
Cem Yuksel
345 views • 2 years ago
Oscar Gonzalez-Recio
3 views • 2 years ago
Please pick a style:
Petra E Vértes. (2021, Nov 9).Morphometric Similarity Networks Detect Microscale Cortical Organisation And Predict Inter-Individual Cognitive Variation[Video]. Scitok. https://scitok.com/project/p/0f13940d
Seidlitz Jakob. "Morphometric Similarity Networks Detect Microscale Cortical Organisation And Predict Inter-Individual Cognitive Variation" Scitok, uploaded by E Vértes Petra, 9 Nov, 2021, https://scitok.com/project/p0f13940d
Petra E Vértes. "Morphometric Similarity Networks Detect Microscale Cortical Organisation And Predict Inter-Individual Cognitive Variation" Scitok. (Nov 9, 2021). https://scitok.com/project/p/0f13940d
Petra E Vértes (Nov 9, 2021). Morphometric Similarity Networks Detect Microscale Cortical Organisation And Predict Inter-Individual Cognitive Variation Scitok. https://scitok.com/project/p/0f13940d
Petra E Vértes. Morphometric Similarity Networks Detect Microscale Cortical Organisation And Predict Inter-Individual Cognitive Variation[video]. 2021 Nov 9. https://scitok.com/project/p/0f13940d
@online{al2006link, title={ Morphometric Similarity Networks Detect Microscale Cortical Organisation And Predict Inter-Individual Cognitive Variation }, author={ E Vértes, Petra }, organization={Scitok}, month={ Nov }, day={ 9 }, year={ 2021 }, url = {https://scitok.com/project/p/0f13940d}, }