Author(s)
Loren Frank
Professor at University of California, San Francisco
Field of Study: Biology , Published 30 Projects
Animal Behavior And Cognition Real Time Sharp Wave Ripple Theta Oscillations Public Speaking
Content
The receptive field of a neuron describes the regions of a stimulus space where the neuron is consistently active. Sparse spiking outside of the receptive field is often considered to be noise, rather than a reflection of information processing. Whether this characterization is accurate remains unclear. We therefore contrasted the sparse, temporally isolated spiking of hippocampal CA1 place cells to the consistent, temporally adjacent spiking seen within their spatial receptive fields ("place fields"). We found that isolated spikes, which occur during locomotion, are more strongly phase coupled to hippocampal theta oscillations than adjacent spikes and, surprisingly, transiently express coherent representations of non-local spatial representations. Further, prefrontal cortical activity is coordinated with, and can predict the occurrence of future isolated spiking events. Rather than local noise within the hippocampus, sparse, isolated place cell spiking reflects a coordinated cortical-hippocampal process consistent with the generation of non-local scenario representations during active navigation.
More Projects
Loren Frank
13 views • 2 years ago
Global Immunotalks
390 views • 2 years ago
Laurel Yohe
2 views • 2 years ago
Global Immunotalks
130 views • 2 years ago
Jignesh H. Parmar
0 views • 2 years ago
Winston A. Haynes
0 views • 2 years ago
Noam Mazor
0 views • 2 years ago
Global Immunotalks
182 views • 2 years ago
Cem Yuksel
345 views • 2 years ago
Oscar Gonzalez-Recio
3 views • 2 years ago
Please pick a style:
Loren Frank. (2021, Nov 7).Prefrontal cortical activity predicts the extra-place field spiking of hippocampal place cells[Video]. Scitok. https://scitok.com/project/p/46b0e825
Y Yu Jai. "Prefrontal cortical activity predicts the extra-place field spiking of hippocampal place cells" Scitok, uploaded by Frank Loren, 7 Nov, 2021, https://scitok.com/project/p46b0e825
Loren Frank. "Prefrontal cortical activity predicts the extra-place field spiking of hippocampal place cells" Scitok. (Nov 7, 2021). https://scitok.com/project/p/46b0e825
Loren Frank (Nov 7, 2021). Prefrontal cortical activity predicts the extra-place field spiking of hippocampal place cells Scitok. https://scitok.com/project/p/46b0e825
Loren Frank. Prefrontal cortical activity predicts the extra-place field spiking of hippocampal place cells[video]. 2021 Nov 7. https://scitok.com/project/p/46b0e825
@online{al2006link, title={ Prefrontal cortical activity predicts the extra-place field spiking of hippocampal place cells }, author={ Frank, Loren }, organization={Scitok}, month={ Nov }, day={ 7 }, year={ 2021 }, url = {https://scitok.com/project/p/46b0e825}, }