Author(s)
Jiandong Zhou
Published 16 Projects
Infectious Diseases Heart Failure Cardiovascular Medicine Risk Stratification Frailty Score
Sharen Lee
Published 16 Projects
Infectious Diseases Heart Failure Cardiovascular Medicine Risk Stratification Frailty Score
William KK Wu
Published 6 Projects
COVID-19 Infectious Diseases Key Words Cardiovascular Medicine Angiotensin Receptor Blockers
Tong Liu
Published 16 Projects
Infectious Diseases Heart Failure Cardiovascular Medicine Risk Stratification Frailty Score
Zhidong Cao
Published 3 Projects
COVID-19 Infectious Diseases Key Words Angiotensin Receptor Blockers Mortality
Dajun Zeng
Published 3 Projects
COVID-19 Infectious Diseases Key Words Angiotensin Receptor Blockers Mortality
Bernard Man Yung Cheung
Published 23 Projects
Infectious Diseases Heart Failure Cardiovascular Medicine Frailty Score COVID-19
Bernard Man Yung Cheung
Published 23 Projects
Infectious Diseases Heart Failure Cardiovascular Medicine Frailty Score COVID-19
Content
BackgroundRecent studies have reported numerous significant predictors for adverse outcomes in COVID-19 disease. However, there have been few simple clinical risk score for prompt risk stratification. The objective is to develop a simple risk score for severe COVID-19 disease using territory-wide healthcare data based on simple clinical and laboratory variables. MethodsConsecutive patients admitted to Hong Kongs public hospitals between 1st January and 22nd August 2020 diagnosed with COVID-19, as confirmed by RT-PCR, were included. The primary outcome was composite intensive care unit admission, need for intubation or death with follow-up until 8th September 2020. ResultsCOVID-19 testing was performed in 237493 patients and 4445 patients (median age 44.8 years old, 95% CI: [28.9, 60.8]); 50% male) were tested positive. Of these, 212 patients (4.8%) met the primary outcome. A risk score including the following components was derived from Cox regression: gender, age, hypertension, stroke, diabetes mellitus, ischemic heart disease/heart failure, respiratory disease, renal disease, increases in neutrophil count, monocyte count, sodium, potassium, urea, alanine transaminase, alkaline phosphatase, high sensitive troponin-I, prothrombin time, activated partial thromboplastin time, D-dimer and C-reactive protein, as well as decreases in lymphocyte count, base excess and bicarbonate levels. The model based on test results taken on the day of admission demonstrated an excellent predictive value. Incorporation of test results on successive time points did not further improve risk prediction. ConclusionsA simple clinical score accurately predicted severe COVID-19 disease, even without including symptoms, blood pressure or oxygen status on presentation, or chest radiograph results.
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Gary Tse. (2021, Nov 8).Development of a predictive risk model for severe COVID-19 disease using population-based administrative data[Video]. Scitok. https://scitok.com/project/p/766e06cc
Zhou Jiandong. "Development of a predictive risk model for severe COVID-19 disease using population-based administrative data" Scitok, uploaded by Tse Gary, 8 Nov, 2021, https://scitok.com/project/p766e06cc
Gary Tse. "Development of a predictive risk model for severe COVID-19 disease using population-based administrative data" Scitok. (Nov 8, 2021). https://scitok.com/project/p/766e06cc
Gary Tse (Nov 8, 2021). Development of a predictive risk model for severe COVID-19 disease using population-based administrative data Scitok. https://scitok.com/project/p/766e06cc
Gary Tse. Development of a predictive risk model for severe COVID-19 disease using population-based administrative data[video]. 2021 Nov 8. https://scitok.com/project/p/766e06cc
@online{al2006link, title={ Development of a predictive risk model for severe COVID-19 disease using population-based administrative data }, author={ Tse, Gary }, organization={Scitok}, month={ Nov }, day={ 8 }, year={ 2021 }, url = {https://scitok.com/project/p/766e06cc}, }