Author(s)
Karla C. Hernández Ramos
Published 1 Project
Introduction Development Cell Environment Interaction Active Matter Biophysics
Edna RodrĂguez-Sánchez
Published 1 Project
Introduction Development Cell Environment Interaction Active Matter Biophysics
Juan Antonio Arias Del Angel
Published 1 Project
Introduction Development Cell Environment Interaction Active Matter Biophysics
Alejandro V. Arzola
Published 1 Project
Introduction Development Cell Environment Interaction Active Matter Biophysics
Mariana BenĂtez
Published 1 Project
Introduction Development Cell Environment Interaction Active Matter Biophysics
Ana Elena Escalante
Published 1 Project
Introduction Development Cell Environment Interaction Active Matter Biophysics
Alessio Franci
Published 1 Project
Introduction Development Cell Environment Interaction Active Matter Biophysics
Giovanni Volpe
Published 5 Projects
Neuroscience Introduction Development Cell Environment Interaction Active Matter
Content
Video Abstract (AI generated) (01:16) Paper Preprint Supplementary material (github,"") (github,"")The social soil-dwelling bacteria Myxococcus xanthus can form multicellular structures, known as fruiting bodies. Experiments in homogeneous environments have shown that this process is affected by the physico-chemical properties of the substrate, but they have largely neglected the role of complex topographies. We experimentally demonstrate that the topography alters single-cell motility and multicellular organization in M. xanthus. In topographies realized by randomly placing silica particles over agar plates, we observe that the cells interaction with particles drastically modifies the dynamics of cellular aggregation, leading to changes in the number, size and shape of the fruiting bodies, and even to arresting their formation in certain conditions. We further explore this type of cell-particle interaction in a minimal computational model. These results provide fundamental insights into how the environment topography influences the emergence of complex multicellular structures from single cells, which is a fundamental problem of biological, ecological and medical relevance.
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Giovanni Volpe. (2021, Oct 30).The environment topography alters the transition from single-cell populations to multicellular structures in Myxococcus xanthus[Video]. Scitok. https://scitok.com/project/p/cb03d0de
C. Hernández Ramos Karla. "The environment topography alters the transition from single-cell populations to multicellular structures in Myxococcus xanthus" Scitok, uploaded by Volpe Giovanni, 30 Oct, 2021, https://scitok.com/project/pcb03d0de
Giovanni Volpe. "The environment topography alters the transition from single-cell populations to multicellular structures in Myxococcus xanthus" Scitok. (Oct 30, 2021). https://scitok.com/project/p/cb03d0de
Giovanni Volpe (Oct 30, 2021). The environment topography alters the transition from single-cell populations to multicellular structures in Myxococcus xanthus Scitok. https://scitok.com/project/p/cb03d0de
Giovanni Volpe. The environment topography alters the transition from single-cell populations to multicellular structures in Myxococcus xanthus[video]. 2021 Oct 30. https://scitok.com/project/p/cb03d0de
@online{al2006link, title={ The environment topography alters the transition from single-cell populations to multicellular structures in Myxococcus xanthus }, author={ Volpe, Giovanni }, organization={Scitok}, month={ Oct }, day={ 30 }, year={ 2021 }, url = {https://scitok.com/project/p/cb03d0de}, }