Neural Activity Patterns Underlying Spatial Coding in the Hippocampus

32 views • May 18, 2021


Author Name


Loren Frank

Professor at University of California, San Francisco

Field of Study: Biology , Published 30 Projects

Animal Behavior And Cognition Real Time Sharp Wave Ripple Theta Oscillations Public Speaking

Add New Author

The hippocampus is well known as a central site for memory processing-critical for storing and later retrieving the experiences events of daily life so they can be used to shape future behavior. Much of what we know about the physiology underlying hippocampal function comes from spatial navigation studies in rodents, which have allowed great strides in understanding how the hippocampus represents experience at the cellular level. However, it remains a challenge to reconcile our knowledge of spatial encoding in the hippocampus with its demonstrated role in memory-dependent tasks in both humans and other animals. Moreover, our understanding of how networks of neurons coordinate their activity within and across hippocampal subregions to enable the encoding, consolidation, and retrieval of memories is incomplete. In this chapter, we explore how information may be represented at the cellular level and processed via coordinated patterns of activity throughout the subregions of the hippocampal network.

Neuroscience 179 Projects
Place Cells
Place Cells 3 Projects
Hippocampus 13 Projects
Learning 4 Projects
Sharp-Wave Ripples
Sharp-Wave Ripples 2 Projects
Spatial Coding
Spatial Coding 1 Project
Theta Oscillations
Theta Oscillations 1 Project
Theta Wave
Theta Wave 1 Project
Memory 8 Projects