Author(s)
Loren Frank
Professor at University of California, San Francisco
Field of Study: Biology , Published 30 Projects
Animal Behavior And Cognition Real Time Sharp Wave Ripple Theta Oscillations Public Speaking
Content
Video Abstract (AI generated) (01:20) Paper Preprint NeuronThe brain is a massive neuronal network, organized into anatomically distributed sub-circuits, with functionally relevant activity occurring at timescales ranging from milliseconds to months. Current methods to monitor neural activity, however, lack the necessary conjunction of anatomical spatial coverage, temporal resolution, and long-term stability to measure this distributed activity. Here we introduce a large-scale, multi-site recording platform that integrates polymer electrodes with a modular stacking headstage design supporting up to 1024 recording channels in freely behaving rats. This system can support months-long recordings from hundreds of well-isolated units across multiple brain regions. Moreover, these recordings are stable enough to track 25% of single units for over a week. This platform enables large-scale electrophysiological interrogation of the fast dynamics and long-timescale evolution of anatomically distributed circuits, and thereby provides a new tool for understanding brain activity.
More Projects
Loren Frank
13 views • 2 years ago
Global Immunotalks
390 views • 3 years ago
Laurel Yohe
2 views • 2 years ago
Global Immunotalks
130 views • 3 years ago
Jignesh H. Parmar
0 views • 2 years ago
Winston A. Haynes
0 views • 2 years ago
Noam Mazor
0 views • 2 years ago
Global Immunotalks
182 views • 3 years ago
Cem Yuksel
345 views • 2 years ago
Oscar Gonzalez-Recio
3 views • 2 years ago
Please pick a style:
Loren Frank. (2021, Nov 7).High-density, long-lasting, and multi-region electrophysiological recordings using polymer electrode arrays[Video]. Scitok. https://scitok.com/project/p/fbbaecec
E Chung Jason. "High-density, long-lasting, and multi-region electrophysiological recordings using polymer electrode arrays" Scitok, uploaded by Frank Loren, 7 Nov, 2021, https://scitok.com/project/pfbbaecec
Loren Frank. "High-density, long-lasting, and multi-region electrophysiological recordings using polymer electrode arrays" Scitok. (Nov 7, 2021). https://scitok.com/project/p/fbbaecec
Loren Frank (Nov 7, 2021). High-density, long-lasting, and multi-region electrophysiological recordings using polymer electrode arrays Scitok. https://scitok.com/project/p/fbbaecec
Loren Frank. High-density, long-lasting, and multi-region electrophysiological recordings using polymer electrode arrays[video]. 2021 Nov 7. https://scitok.com/project/p/fbbaecec
@online{al2006link, title={ High-density, long-lasting, and multi-region electrophysiological recordings using polymer electrode arrays }, author={ Frank, Loren }, organization={Scitok}, month={ Nov }, day={ 7 }, year={ 2021 }, url = {https://scitok.com/project/p/fbbaecec}, }